Drugs / Universal Donor (UD) Transforming growth factor beta imprinting (TGFβi) Natural Killer (NK) Cells
last change May 2024 re-read 3 minutes ago

Universal Donor (UD) Transforming growth factor beta imprinting (TGFβi) Natural Killer (NK) Cells

Cell therapy

Developed for
brain cancer · childhood malignant neoplasm
Investigated by
CureSearch · Nationwide Children's Hospital · Rally Foundation · Sabine Mueller, MD, PhD · Tommy Strong Foundation · Washington University School of Medicine

Trials 1

2025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05887882 May 2024 → Dec 2027 brain cancer, childhood malignant neoplasm Sabine Mueller, MD, PhD Suspended No outcome recorded Stop: Enrollment

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Universal Donor (UD) Transforming growth factor beta imprinting (TGFβi) Natural Killer (NK) Cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT05887882 ↗
Action Deplete “Natural killer (NK) cells are immune cells that recognize and get rid of abnormal cells in the body, including tumor cells and cells infected by viruses.” NCT05887882 ↗
Modality Cell therapy “ex vivo expanded natural killer cells” NCT05887882 ↗
Route Other “administered intra-tumoral via an Ommaya reservoir” NCT05887882 ↗