Drugs / Agrippal
last change Jul 2019 re-read 2 minutes ago

Agrippal

Vaccine

Developed for
influenza
Investigated by
Novartis Vaccines · Novartis · Chiron s.r.l. Beijing Representative Office · Crucell Holland BV · University of Oxford

Trials 7 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 22 trials
Phase 2 NCT01682369 Sep 2012 → Feb 2013 influenza University of Oxford Completed No outcome recorded
Phase 2 NCT01636102 Jul 2012 influenza Novartis Vaccines Completed No outcome recorded
Phase 34 trials
Phase 3 NCT01310400 Oct 2009 → Jan 2010 influenza Crucell Holland BV Completed No outcome recorded
Phase 3 NCT00841763 Oct 2008 → Apr 2009 influenza Novartis Completed No outcome recorded
Phase 3 NCT00464672 Apr → Jul 2007 influenza Novartis Completed No outcome recorded
Phase 3 NCT00310648 Jan 2006 → ? influenza Novartis Completed No outcome recorded
Phase 41 trial
Phase 4 NCT00560066 Nov 2007 → Jul 2008 influenza Novartis Vaccines Completed No outcome recorded
Also used as a comparator or background therapy in 5 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03893669 Comparator Sep → Oct 2012 SK Chemicals Co., Ltd. Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT03826719 Comparator Feb → Mar 2014 influenza SK Chemicals Co., Ltd. Completed No outcome recorded
Phase 31 trial
Phase 3 NCT03704740 Comparator Oct 2018 → Jul 2019 influenza SK Bioscience Co., Ltd. Completed No outcome recorded
Phase 41 trial
Phase 4 NCT02686398 Comparator Oct 2013 → Nov 2014 end stage renal failure, influenza Korea University Guro Hospital Completed No outcome recorded
Phase not applicable1 trial
NCT01771367 Comparator Jan → Jun 2013 University of Surrey Completed No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 12 sources stand behind the page.

FieldValueCited text
Known as Agrippal “A Phase II Open Label, Uncontrolled, Multicenter Study to Evaluate Safety and Immunogenicity of a Surface Antigen, Inactivated, Influenza Vaccine (Agrippal®), Formulation 2012/2013” NCT01636102
11

“a primarily European-marketed trivalent vaccine (Agrippal®, Novartis Vaccines), and a predominantly U.S.-marketed control trivalent vaccine (Fluvirin®, Novartis Vaccines)” PMID 22691101 Jun 2012

“Trivalent Subunit Influenza Vaccine Produced Either in Mammalian Cell Culture (Optaflu®) or in Embryonated Hen Eggs (Agrippal®)” NCT00560066

“initial dose of a licensed, non-adjuvanted, trivalent, seasonal influenza vaccine (Agrippal(®)) on Day 1” PMID 22192847 Dec 2011

“a non-adjuvanted subunit influenza vaccine (Subunit; Agrippal, Novartis Vaccines)” PMID 18289372 Feb 2008

“Administer a dose of 0.25ml of vaccine TIV (Agrippal)” NCT01682369

NCT03826719

NCT03893669

NCT02686398

NCT01310400

NCT01771367

NCT03704740

Modality Vaccine “a non-adjuvanted subunit influenza vaccine (Subunit; Agrippal, Novartis Vaccines)” PMID 18289372 Feb 2008
Route Intramuscular “Adolescents and adults received one dose of vaccine intramuscularly, whereas children aged 3-8 years received two vaccine doses, administered 4 wk apart” PMID 22691101 Jun 2012