Drugs / QAV680
last change Sep 2010 re-read 9 days ago

QAV680

also known as NVP-QAV680 · QAV690 FREE ACID

Small molecule targets PTGDR2 via inhibition

Developed for
asthma · allergic rhinitis · seasonal allergic rhinitis
Investigated by
Novartis · Novartis Pharmaceuticals

Trials 4

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01103050 Mar → Jul 2010 allergic rhinitis Novartis Pharmaceuticals Completed No outcome recorded
Phase 2 NCT01103037 Mar → Sep 2010 asthma Novartis Pharmaceuticals Terminated No outcome recorded
Phase 2 NCT00814216 Dec 2008 → Oct 2009 asthma Novartis Completed No outcome recorded
Phase 2 NCT00784732 Sep → Dec 2008 seasonal allergic rhinitis Novartis Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as QAV680 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00784732 ↗
3

NCT01103050 ↗

NCT01103037 ↗

NCT00814216 ↗

Known as NVP-QAV680 ChEMBL registry synonym — accepted as the source's own label CHEMBL2442750 ↗
Known as QAV690 FREE ACID ChEMBL registry synonym — accepted as the source's own label CHEMBL2442750 ↗
Action Inhibit “G protein-coupled receptor 44 antagonist” CHEMBL2442750 ↗
1

“CRTh2 Receptor Antagonist, QAV680” NCT00784732 ↗

Modality Small molecule — CHEMBL2442750 ↗
Route Oral “oral QAV680” NCT00814216 ↗
Target PTGDR2 “G protein-coupled receptor 44 antagonist” CHEMBL2442750 ↗