Drugs / ETALOCIB
last change Dec 2005 re-read 3 minutes ago

ETALOCIB

also known as LY293111 · LY-193111 · VML 295

Small molecule targets LTB4R, PPARG via inhibition / activation

Developed for
cancer of unknown primary site · malignant pancreatic neoplasm · non-small cell lung carcinoma
Investigated by
Eli Lilly and Company · Memorial Sloan Kettering Cancer Center · National Cancer Institute (NCI)

Trials 3

2000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00006375 Jun 2000 → Feb 2003 cancer of unknown primary site Memorial Sloan Kettering Cancer Center Completed No outcome recorded
Phase 22 trials
Phase 2 NCT00069875 Sep 2003 → Dec 2005 non-small cell lung carcinoma Eli Lilly and Company Completed No outcome recorded
Phase 2 NCT00055250 Jan 2003 → Oct 2005 malignant pancreatic neoplasm Eli Lilly and Company Completed No outcome recorded

Evidence & citations 10 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as ETALOCIB ChEMBL registry synonym — accepted as the source's own label CHEMBL329123 ↗
Known as LY-193111 ChEMBL registry synonym — accepted as the source's own label CHEMBL329123 ↗
Known as LY293111 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00069875 ↗
2

NCT00006375 ↗

NCT00055250 ↗

Known as VML 295 ChEMBL registry synonym — accepted as the source's own label CHEMBL329123 ↗
Action Activate “Peroxisome proliferator-activated receptor gamma agonist” CHEMBL329123 ↗
Action Inhibit “Leukotriene B4 receptor 1 antagonist” CHEMBL329123 ↗
Modality Small molecule — CHEMBL329123 ↗
Route Oral “Patients receive oral LY293111 twice daily.” NCT00006375 ↗
Target LTB4R “Leukotriene B4 receptor 1 antagonist” CHEMBL329123 ↗
Target PPARG “Peroxisome proliferator-activated receptor gamma agonist” CHEMBL329123 ↗