Drugs / SIM1803-1A
last change Jan 2024 re-read 3 minutes ago

SIM1803-1A

targets ALK, NTRK1, NTRK2, NTRK3, ROS1 via inhibition

Developed for
NTRK fusion positive cancer
Investigated by
Jiangsu Simcere Pharmaceutical Co., Ltd.

Trials 1

202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04671849 Dec 2020 → Sep 2022 NTRK fusion positive cancer Jiangsu Simcere Pharmaceutical Co., Ltd. Unknown No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as SIM1803-1A ClinicalTrials.gov intervention name — accepted as the source's own label NCT04671849 ↗
Action Inhibit “SIM1803-1A is a drug that blocks the actions of these NTRK/ ROS1 /ALK genes in cancer cells” NCT04671849 ↗
Target ALK “The cancer must have a change in a particular gene (NTRK1, NTRK2, NTRK3, ROS1 or ALK). SIM1803-1A is a drug that blocks the actions of these NTRK/ ROS1 /ALK genes in cancer...” NCT04671849 ↗
Target NTRK1 “The cancer must have a change in a particular gene (NTRK1, NTRK2, NTRK3, ROS1 or ALK). SIM1803-1A is a drug that blocks the actions of these NTRK/ ROS1 /ALK genes in cancer...” NCT04671849 ↗
Target NTRK2 “The cancer must have a change in a particular gene (NTRK1, NTRK2, NTRK3, ROS1 or ALK). SIM1803-1A is a drug that blocks the actions of these NTRK/ ROS1 /ALK genes in cancer...” NCT04671849 ↗
Target NTRK3 “The cancer must have a change in a particular gene (NTRK1, NTRK2, NTRK3, ROS1 or ALK). SIM1803-1A is a drug that blocks the actions of these NTRK/ ROS1 /ALK genes in cancer...” NCT04671849 ↗
Target ROS1 “The cancer must have a change in a particular gene (NTRK1, NTRK2, NTRK3, ROS1 or ALK). SIM1803-1A is a drug that blocks the actions of these NTRK/ ROS1 /ALK genes in cancer...” NCT04671849 ↗