Drugs / Autologous cord blood
Autologous cord blood
also known as
autologous umbilical cord blood · Autologous human umbilical cord blood · ACB · Autlogous UCB infusion · hUCB · UCB
Trials 13 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 18 trials | ||||||
| Phase 1 | NCT04768816 | Jul 2019 → Dec 2022 | — | Guangdong Women and Children Hospital | Unknown | No outcome recorded |
| Phase 1 | NCT04007224 | Jan 2019 → Jun 2023 | autism spectrum disorder | Fundatia Bio-Forum | Completed | No outcome recorded |
| Phase 1 | NCT03526588 | Aug 2018 → Jul 2022 | congenital diaphragmatic hernia | The University of Texas Health Science Center, Houston | Terminated | No outcome recorded |
| Phase 1 | NCT03791372 | Oct 2017 → Oct 2020 | — | Guangdong Women and Children Hospital | Unknown | No outcome recorded |
| Phase 1 | NCT02176317 | Jun 2014 → Dec 2015 | autism spectrum disorder | Duke University | Completed | No outcome recorded |
| Phase 1 | NCT01445041 | Sep 2011 → Apr 2016 | hypoplastic left heart syndrome | Michael Cotten | Terminated | No outcome recorded |
| Phase 1 | NCT01649648 | Sep 2011 → Nov 2013 | brain hypoxia - ischemia | National University Hospital, Singapore | Completed | No outcome recorded |
| Phase 1 | NCT01343394 | Apr 2011 → Jan 2013 | hearing loss disorder | Aryn Knight | Withdrawn | No outcome recorded |
| Phase 1/24 trials | ||||||
| Phase 1/2 | NCT03558269 | Feb 2019 → May 2021 | brain injury, cardiogenic shock, congenital heart disease | Sheba Medical Center | Unknown | No outcome recorded |
| Phase 1/2 | NCT02551003 | Sep 2015 → Dec 2016 | brain hypoxia - ischemia, cerebral infarction | Children's Hospital of Fudan University | Withdrawn | No outcome recorded |
| Phase 1/2 | NCT02460484 | Apr 2015 → Jun 2022 | pediatric arterial ischemic stroke | James Baumgartner, MD | Withdrawn | No outcome recorded |
| Phase 1/2 | NCT01251003 | Jan 2011 → Dec 2014 | traumatic brain injury | Charles Cox | Withdrawn | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT04243382 | Feb 2020 → Dec 2024 | autism spectrum disorder | Sheba Medical Center | Unknown | No outcome recorded |
Also used as a comparator or background therapy in 1 trial
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 2 | NCT01147653 Comparator | Jun 2010 → Mar 2016 | spastic cerebral palsy | Joanne Kurtzberg, MD | Completed | No outcome recorded |
Evidence & citations 9 cited values
Every value below carries the sentence it was read from. 14 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Autologous cord blood | “After demonstrating safety, we conducted a phase II trial of autologous cord blood (ACB) infusion in children with CP to test whether ACB could improve function” PMID 29080265 ↗ Oct 2017 |
| Known as | ACB | “After demonstrating safety, we conducted a phase II trial of autologous cord blood (ACB) infusion in children with CP to test whether ACB could improve function” PMID 29080265 ↗ Oct 2017 |
| Known as | Autlogous UCB infusion | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03558269 ↗ |
| Known as | Autologous human umbilical cord blood | “Autologous human umbilical cord blood (hUCB) stored at Cord Blood Registry will be given to children who have suffered from a Perinatal Arterial Ischemic Stroke.” NCT02460484 ↗ |
| Known as | autologous umbilical cord blood | “The aim of the study is to evaluate the feasibility and safety and efficacy of collecting and infusing autologous umbilical cord blood (UCB) in newborn infants with hypoplastic...” NCT03558269 ↗ |
| Known as | hUCB | “Autologous human umbilical cord blood (hUCB) stored at Cord Blood Registry will be given to children who have suffered from a Perinatal Arterial Ischemic Stroke.” NCT02460484 ↗ |
| Known as | UCB | “The aim of the study is to evaluate the feasibility and safety and efficacy of collecting and infusing autologous umbilical cord blood (UCB) in newborn infants with hypoplastic...” NCT03558269 ↗ |
| Modality | Cell therapy | “single intravenous infusion of 1-5 × 107 total nucleated cells per kilogram of ACB” PMID 29080265 ↗ Oct 2017 |
| Route | Intravenous | “single intravenous infusion of 1-5 × 107 total nucleated cells per kilogram of ACB” PMID 29080265 ↗ Oct 2017 |