Drugs / lanicemine

Trials 10 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 16 trials
Phase 1 NCT03166501 Sep 2018 → Nov 2019 depressive disorder, post-traumatic stress disorder Baylor College of Medicine Completed No outcome recorded
Phase 1 NCT01130909 May 2010 → Jan 2011 AstraZeneca Terminated No outcome recorded
Phase 1 NCT01069822 Feb → May 2010 AstraZeneca Completed No outcome recorded
Phase 1 NCT01046630 Dec 2009 → Mar 2011 depressive disorder AstraZeneca Completed No outcome recorded
Phase 1 NCT00963365 Nov 2008 → Feb 2009 AstraZeneca Withdrawn No outcome recorded
Phase 1 NCT00785915 Nov 2008 → Mar 2009 AstraZeneca Completed No outcome recorded
Phase 24 trials
Phase 2 NCT01482221 Dec 2011 → Aug 2013 major depressive disorder AstraZeneca Completed No outcome recorded
Phase 2 NCT00986479 Dec 2009 → Dec 2011 major depressive disorder AstraZeneca Completed No outcome recorded
Phase 2 NCT00781742 Oct 2008 → Mar 2010 major depressive disorder AstraZeneca Completed No outcome recorded
Phase 2 NCT00491686 Jul → Nov 2007 major depressive disorder AstraZeneca Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 12 sources stand behind the page.

FieldValueCited text
Known as lanicemine “Using quantitative electroencephalography (qEEG) to objectively align doses of a low-trapping NMDA channel blocker, AZD6765 (lanicemine), to that of ketamine, we demonstrate...” PMID 24126931 Oct 2013
2

“Intravenous infusion of lanicemine (formerly AZD6765), a low trapping non-selective N-methyl-D-aspartate (NMDA) receptor antagonist, induces antidepressant effects with a...” PMID 27133029 Apr 2016

NCT03166501

Known as AR-R15896AR ChEMBL registry synonym — accepted as the source's own label CHEMBL467084
Known as AZD6765 “Intravenous infusion of lanicemine (formerly AZD6765), a low trapping non-selective N-methyl-D-aspartate (NMDA) receptor antagonist, induces antidepressant effects with a...” PMID 27133029 Apr 2016
8

NCT01482221

NCT01130909

NCT00963365

NCT00491686

NCT00785915

NCT00781742

NCT01069822

NCT00986479

Known as Lanicemina ChEMBL registry synonym — accepted as the source's own label CHEMBL467084
Action Inhibit “a low-trapping NMDA channel blocker” PMID 24126931 Oct 2013
Modality Small molecule CHEMBL467084
Route Intravenous intravenous infusion” NCT00491686