Drugs / Lartesertib
last change Jun 2026 re-read 2 minutes ago

Lartesertib

also known as M4076

Small molecule targets ATM via inhibition

Developed for
cancer · cancer of unknown primary site · ovarian carcinoma
Investigated by
EMD Serono Research & Development Institute, Inc. · Merck KGaA, Darmstadt, Germany

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT05396833 Jun 2022 → Jan 2027 expected cancer of unknown primary site EMD Serono Research & Development Institute, Inc. Active not recruiting No outcome recorded
Phase 1 NCT04882917 May 2021 → Mar 2023 cancer EMD Serono Research & Development Institute, Inc. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT06433219 Oct 2024 → Jun 2026 overdue ovarian carcinoma EMD Serono Research & Development Institute, Inc. Active not recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Lartesertib ClinicalTrials.gov intervention name — accepted as the source's own label NCT05396833
1

NCT06433219

Known as M4076 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04882917
Action Inhibit “ATM Inhibitor M4076” NCT04882917
Modality Small molecule CHEMBL5314413
Route Oral “M4076 was administered orally.” NCT04882917
Target ATM ATM Inhibitor M4076” NCT04882917