Drugs / MB-dNPM1-TCR.1
last change Aug 2024 re-read 3 minutes ago

MB-dNPM1-TCR.1

Cell therapy

Developed for
acute myeloid leukemia
Investigated by
Miltenyi Biomedicine GmbH

Trials 1

2025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT06424340 Aug 2024 → Jun 2028 expected acute myeloid leukemia Miltenyi Biomedicine GmbH Recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as MB-dNPM1-TCR.1 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06424340 ↗
Action Deplete “The dNPM1-TCR transduced T cells target specifically the HLA/dNPM1 peptide complex on the cell surface of leukemic myeloid cells and eliminate these.” NCT06424340 ↗
Modality Cell therapy “ex vivo expanded autologous T cells genetically modified to express a T cell receptor (TCR)” NCT06424340 ↗