Drugs / CIMAvax-EGF
last change Feb 2026 re-read 2 minutes ago

CIMAvax-EGF

also known as CIMAvax

Vaccine

Developed for
colorectal cancer · head and neck squamous cell carcinoma · non-small cell lung carcinoma · non-small cell squamous lung carcinoma
Investigated by
Roswell Park Cancer Institute

Trials 3 · a red edge is where a trial was stopped

2017201820192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 02 trials
Phase 0 NCT06011772 Dec 2023 → Feb 2026 overdue colorectal cancer Roswell Park Cancer Institute Active not recruiting No outcome recorded
Phase 0 NCT04298606 Nov 2021 → Dec 2025 chronic obstructive pulmonary disease, non-small cell lung carcinoma, pneumonia Roswell Park Cancer Institute Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT02955290 Dec 2016 → May 2025 overdue head and neck squamous cell carcinoma, non-small cell squamous lung carcinoma Roswell Park Cancer Institute Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as CIMAvax-EGF “This early phase I trial studies the side effects of a vaccine called CIMAvax-EGF and to see how well it works in preventing lung cancer from developing in patients at high...” NCT04298606
1

“EGF-Depleting Therapy CIMAvax-EGF in Combination With Standard Therapy for RAS- and BRAF Wild-Type Metastatic Colorectal Cancer” NCT06011772

Known as CIMAvax “EGF Vaccine CIMAvaxNCT02955290
Action Inhibit “CIMAvax-EGF vaccine works by causing the body to make antibodies against EGF” NCT04298606
Modality Vaccine “EGF Vaccine CIMAvax” NCT02955290
Route Intramuscular “Given CIMAvax IM” NCT02955290