Drugs / Suvratoxumab
last change Jun 2026 re-read 3 minutes ago

Suvratoxumab

also known as MEDI4893

Monoclonal antibody

Developed for
staphylococcus aureus infection · staphylococcus aureus pneumonia
Investigated by
Aridis Pharmaceuticals, Inc. · AstraZeneca · Parexel

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT07612813 Jun 2026 → Sep 2027 expected staphylococcus aureus infection AstraZeneca Recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT05331885 Sep 2022 → Jul 2024 staphylococcus aureus infection Aridis Pharmaceuticals, Inc. Terminated No outcome recorded
Comparator or background therapy2 trials
Phase 1 NCT01769417 Comparator Jan 2013 → May 2014 staphylococcus aureus infection MedImmune LLC Completed No outcome recorded
Phase 2 NCT02296320 Comparator Oct 2014 → Oct 2018 staphylococcus aureus pneumonia MedImmune LLC Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Suvratoxumab “AZD7760, a mAb combination of suvratoxumab (labeled as MEDI4893) and AZD7745” NCT07612813 ↗
1

NCT05331885 ↗

Known as MEDI4893 “AZD7760, a mAb combination of suvratoxumab (labeled as MEDI4893) and AZD7745” NCT07612813 ↗
2

NCT01769417 ↗

NCT02296320 ↗

Action Inhibit “specifically binds to and neutralizes alpha-toxin” PMID 27795368 ↗ Dec 2016
Modality Monoclonal antibody “human monoclonal antibody” NCT01769417 ↗
Route Intravenous “administered as a single IV dose” NCT01769417 ↗