Drugs / MEDI8968
last change Aug 2017 re-read 3 minutes ago

MEDI8968

Monoclonal antibody targets IL1R1

Developed for
chronic obstructive pulmonary disease · hidradenitis suppurativa
Investigated by
AstraZeneca · Covance · ICON plc · MedImmune LLC · PHT Corporation

Trials 2

2012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01838499 May 2013 → Oct 2014 hidradenitis suppurativa AstraZeneca Terminated Missed primary
Phase 2 NCT01448850 Nov 2011 → Feb 2014 chronic obstructive pulmonary disease MedImmune LLC Completed Missed primary

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as MEDI8968 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01448850 ↗
1

NCT01838499 ↗

Modality Monoclonal antibody “MEDI8968, a fully human monoclonal antibody” PMID 28793896 ↗ Aug 2017
Route Intravenous “600 milligram (mg) as intravenous (IV) infusion” NCT01448850 ↗
Target IL1R1 “MEDI8968, a fully human monoclonal antibody, binds selectively to IL-1R1” PMID 28793896 ↗ Aug 2017