Drugs / Brompheniramine
Brompheniramine
also known as
Bromfed · Bromfenex · Bromfeniramina · Brompheniramine maleate · Brompheniramine maleate component of biphetap · Brompheniramine maleate component of bromanate · Brompheniramine maleate component of bromanate dc · Brompheniramine maleate component of bromanate dm · +15 more
Small molecule targets HRH1 via inhibition
Regulatory milestones approvals, filings & regulatory actions · 2 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansion | US (FDA) | DIMETANE | — | 1983-04-15 | fda.gov ↗ |
| Approved | US (FDA) | DIMETANE | — | 1957-08-23 | fda.gov ↗ |
Trials 2 · a red edge is where a trial was stopped
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT00894634 | Mar → Apr 2009 | allergic disease | Wyeth is now a wholly owned subsidiary of Pfizer | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT01393561 | Jul → Oct 2014 | rhinitis | Ache Laboratorios Farmaceuticos S.A. | Completed | No outcome recorded |
Also used as a comparator or background therapy in 2 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 3 | NCT01393548 Background | Aug 2014 → Nov 2016 | rhinitis | Ache Laboratorios Farmaceuticos S.A. | Completed | No outcome recorded |
| Phase 3 | NCT01177852 Comparator | Oct 2011 → Apr 2012 | rhinitis | Ache Laboratorios Farmaceuticos S.A. | Withdrawn | No outcome recorded |
Evidence & citations 28 cited values
Every value below carries the sentence it was read from. 5 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | brompheniramine | “Brompheniramine + phenylephrine” NCT01393561 ↗ |
| Known as | Bromfed | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Bromfenex | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Bromfeniramina | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Brompheniramine maleate | “Brompheniramine maleate oral solution 1 mg/5 mL, single dose” NCT00894634 ↗ |
| Known as | Brompheniramine maleate component of biphetap | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Brompheniramine maleate component of bromanate | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Brompheniramine maleate component of bromanate dc | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Brompheniramine maleate component of bromanate dm | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Brompheniramine maleate component of bromatapp | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Brompheniramine maleate component of bromfed-dm | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Brompheniramine maleate component of dimetane-dc | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Brompheniramine maleate component of dimetane-dx | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Brompheniramine maleate component of dimetapp | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Brompheniramine maleate component of myphetane dc | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Brotane | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Dimegan | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Dimetane | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Dimetane-ten | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Dimetapp | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Dimotane | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Dimotane l.a. | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | Lodrane | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Known as | NSC-758652 | ChEMBL registry synonym — accepted as the source's own label CHEMBL811 ↗ |
| Action | Inhibit | “Histamine H1 receptor antagonist” CHEMBL811 ↗ |
| Modality | Small molecule | — CHEMBL811 ↗ |
| Route | Oral | “Brompheniramine maleate oral solution 1 mg/5 mL, single dose” NCT00894634 ↗ |
| Target | HRH1 | “Histamine H1 receptor antagonist” CHEMBL811 ↗ |