Drugs / UCB-1184197
last change Mar 2013 re-read 3 minutes ago

UCB-1184197

also known as CDP323 · Zaurategrast ethyl ester

Small molecule targets ITGA4 via inhibition

Developed for
multiple sclerosis · relapsing-remitting multiple sclerosis
Investigated by
Biogen · UCB Pharma

Trials 2

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT00726648 Jul 2008 → Mar 2009 relapsing-remitting multiple sclerosis UCB Pharma Completed No outcome recorded
Phase 21 trial
Phase 2 NCT00484536 May 2007 → Nov 2009 multiple sclerosis UCB Pharma Terminated No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as UCB-1184197 ChEMBL registry synonym — accepted as the source's own label CHEMBL4297363 ↗
Known as CDP323 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00726648 ↗
1

NCT00484536 ↗

Known as Zaurategrast ethyl ester ChEMBL registry synonym — accepted as the source's own label CHEMBL4297363 ↗
Action Inhibit “CDP323, an oral α4-integrin inhibitor” PMID 23472197 ↗ Mar 2013
1

“Integrin alpha-4 inhibitor” CHEMBL4297363 ↗

Modality Small molecule — CHEMBL4297363 ↗
Route Oral “CDP323, an oral α4-integrin inhibitor” PMID 23472197 ↗ Mar 2013
Target ITGA4 “Integrin alpha-4 inhibitor” CHEMBL4297363 ↗