Drugs / CD8 Depleted, Non-engrafting,HLA mismatched unrelated donor lymphocytes
last change Jul 2024 re-read 3 minutes ago

CD8 Depleted, Non-engrafting,HLA mismatched unrelated donor lymphocytes

Cell therapy

Developed for
acute myeloid leukemia · myelodysplastic syndrome
Investigated by
H. Lee Moffitt Cancer Center and Research Institute

Trials 1

202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT04620681 Jan 2021 → Jul 2024 acute myeloid leukemia, myelodysplastic syndrome H. Lee Moffitt Cancer Center and Research Institute Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as CD8 Depleted, Non-engrafting,HLA mismatched unrelated donor lymphocytes ClinicalTrials.gov intervention name — accepted as the source's own label NCT04620681 ↗
Known as NE-DLI “This study is attempting to design a therapy called "non-engrafting, CD8 depleted donor lymphocyte infusion" or "NE-DLI" as a treatment for these diseases.” NCT04620681 ↗
Known as non-engrafting, CD8 depleted donor lymphocyte infusion “This study is attempting to design a therapy called "non-engrafting, CD8 depleted donor lymphocyte infusion" or "NE-DLI" as a treatment for these diseases.” NCT04620681 ↗
Modality Cell therapy “Infusion of mononuclear cells, apheresis products depleted of CD8+ T cells using the CliniMACS® system with CliniMACS® CD8 reagent” NCT04620681 ↗