Drugs / HLX53
last change Mar 2025 re-read 2 minutes ago

HLX53

Protein / enzyme biologic targets TIGIT via inhibition

Developed for
hepatocellular carcinoma
Investigated by
Shanghai Henlius Biotech

Trials 2 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05394168 Dec 2022 → Dec 2024 Shanghai Henlius Biotech Unknown No outcome recorded
Phase 21 trial
Phase 2 NCT06349980 Aug 2024 → Feb 2027 expected hepatocellular carcinoma Shanghai Henlius Biotech Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as HLX53 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06349980
1

NCT05394168

Action Inhibit “anti-TIGIT Fc fusion protein” NCT05394168
Modality Protein / enzyme biologic “HLX53 (an anti-TIGIT Fc fusion protein)” NCT05394168
Route Intravenous “administered by intravenous infusion” NCT05394168
Target TIGIT “HLX53 (an Anti-TIGIT Fc Fusion Protein)” NCT06349980