Drugs / Prostaglandin E2
last change Aug 2025 re-read 9 days ago

Prostaglandin E2

also known as Propess
Developed for
preterm premature rupture of the membranes · cervix disorder · pregnancy disorder
Investigated by
Shaare Zedek Medical Center

Trials 1

20172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 41 trial
Phase 4 NCT02801227 Sep 2016 → Sep 2017 preterm premature rupture of the membranes Shaare Zedek Medical Center Unknown No outcome recorded
Comparator or background therapy3 trials
Phase 3 NCT00545194 Comparator Jan 2002 → Oct 2004 cervix disorder French National Institute of Health and Medical Research Withdrawn No outcome recorded Stop: Enrollment
Phase 4 NCT04743297 Comparator Mar 2021 → Jan 2023 preterm premature rupture of the membranes University Medical Centre Maribor Unknown No outcome recorded
— NCT03471858 Comparator Aug 2019 → Aug 2022 pregnancy disorder Ministry of Health, Singapore Completed No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Prostaglandin E2 “Prostaglandin E2 (Prostin®) 3mg tablet, placed high in the vaginal fornix.” NCT03471858 ↗
3

NCT02801227 ↗

NCT04743297 ↗

NCT00545194 ↗

Known as Propess “Propess - Prostaglandin E2 Vaginal Delivery System. Slow intravaginal release of 10 mg dinoprostone at a rate of 0.3 mg/h.” NCT04743297 ↗
Route Other “Intravaginal gel” NCT00545194 ↗