Drugs / Insulin Tregopil
last change Apr 2021 re-read 2 minutes ago

Insulin Tregopil

Protein / enzyme biologic targets INSR via activation

Developed for
type 2 diabetes mellitus · type 1 diabetes mellitus
Investigated by
Biocon Limited

Trials 3 · a red edge is where a trial was stopped

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT03392961 Mar → Jul 2014 type 2 diabetes mellitus Biocon Limited Completed No outcome recorded
Phase 1 NCT01035801 Aug 2010 → Mar 2011 type 1 diabetes mellitus Biocon Limited Terminated No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT03430856 Dec 2017 → Feb 2019 type 2 diabetes mellitus Biocon Limited Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04141423 Comparator Oct 2019 → Apr 2021 type 1 diabetes mellitus Biocon Limited Terminated No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as Insulin Tregopil “This is an open label Phase II/III study to evaluate the efficacy and safety of test drug, Insulin Tregopil (IN-105) compared with Insulin Aspart (IAsp) in Type 2 Diabetes...” NCT03430856
1

“IN-105 (Insulin Tregopil)” NCT03392961

Known as IN-105 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01035801
1

NCT03392961

Known as Insulina tregopilo ChEMBL registry synonym — accepted as the source's own label CHEMBL2108305
Known as Insuline tregopil ChEMBL registry synonym — accepted as the source's own label CHEMBL2108305
Known as Tregopil ClinicalTrials.gov intervention name — accepted as the source's own label NCT03430856
1

NCT04141423

Action Activate “Insulin receptor agonist” CHEMBL2108305
Modality Protein / enzyme biologic “oral insulin tregopil” PMID 31392840 Aug 2019
Route Oral “The purpose of this study is to see whether IN-105 (oral insulin) is able to control increase in blood glucose after eating a meal.” NCT01035801
Target INSR “Insulin receptor agonist” CHEMBL2108305