Drugs / WT1 mRNA-loaded DCs
last change Aug 2025 re-read 2 minutes ago

WT1 mRNA-loaded DCs

also known as WT1/DC

Cell therapy

Developed for
diffuse intrinsic pontine glioma · high grade astrocytic tumor
Investigated by
Kom Op Tegen Kanker · Olivia Hendrickx research Fund vzw · Stichting Semmy · University Hospital, Antwerp

Trials 1 · a red edge is where a trial was stopped

20222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT04911621 Sep 2021 → Aug 2025 diffuse intrinsic pontine glioma, high grade astrocytic tumor University Hospital, Antwerp Completed No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as WT1 mRNA-loaded DCs “intradermal vaccination with autologous WT1 mRNA-loaded DCs weekly (-1 day, +2 days) for 3 weeks” NCT04911621
Known as WT1/DC “assessing the feasibility and safety of WT1 mRNA-loaded DC (WT1/DC) immunotherapy in combination with conventional treatment in pHGG and DIPG” PMID 38503417 Mar 2024
Modality Cell therapy “the manufacturing of autologous WT1/DC vaccines” PMID 38503417 Mar 2024