Drugs / CD33 FPBMC
last change Mar 2026 re-read 3 minutes ago

CD33 FPBMC

also known as CD33Bi FPBMC

Cell therapy targets CD33 via depletion

Developed for
acute myeloid leukemia · myelodysplastic syndrome · myelodysplastic/myeloproliferative neoplasm
Investigated by
University of Virginia

Trials 1

20272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07270978 Mar 2026 → Aug 2028 expected acute myeloid leukemia, myelodysplastic syndrome, myelodysplastic/myeloproliferative neoplasm University of Virginia Recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as CD33 FPBMC ClinicalTrials.gov intervention name — accepted as the source's own label NCT07270978 ↗
Known as CD33Bi FPBMC “combining anti-CD3 x anti-CD33 bispecific antibody (CD33Bi) armed fresh peripheral blood mononuclear cells (CD33Bi FPBMC)” NCT07270978 ↗
Action Deplete “so the T cells can multiply and kill AML/MDS cells.” NCT07270978 ↗
Modality Cell therapy “armed fresh peripheral blood mononuclear cells” NCT07270978 ↗
Route Intravenous “CD33 FPBMC by intravenous infusion” NCT07270978 ↗
Target CD33 “anti-CD3 x anti-CD33 bispecific antibody” NCT07270978 ↗