Drugs / VXM01
last change Dec 2022 re-read 2 minutes ago

VXM01

Vaccine

Developed for
glioblastoma · colorectal cancer · pancreas disorder
Investigated by
Vaximm GmbH · Merck KGaA, Darmstadt, Germany · Pfizer

Trials 4 · a red edge is where a trial was stopped

2012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT02718443 May 2016 → Aug 2017 glioblastoma Vaximm GmbH Completed No outcome recorded
Phase 1 NCT02718430 Feb 2016 → Mar 2018 colorectal cancer Vaximm GmbH Completed No outcome recorded
Phase 1 NCT01486329 Dec 2011 → Oct 2014 pancreas disorder Vaximm GmbH Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT03750071 Nov 2018 → Dec 2021 glioblastoma Vaximm GmbH Unknown No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as VXM01 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03750071
3

NCT02718443

NCT02718430

NCT01486329

Action Inhibit “The immune reaction elicited by VXM01 is expected to disrupt the tumor neovasculature and, consequently, inhibit tumor growth.” PMID 22906006 Aug 2012
Modality Vaccine “The investigational oral DNA vaccine VXM01 targets the vascular endothelial growth factor receptor 2 (VEGFR-2) and uses Salmonella typhi Ty21a as a vector.” PMID 22906006 Aug 2012
Route Oral “The investigational oral DNA vaccine VXM01 targets the vascular endothelial growth factor receptor 2 (VEGFR-2)” PMID 22906006 Aug 2012