Drugs / CART-PSMA-TGFβRDN cells
last change May 2018 re-read 3 minutes ago

CART-PSMA-TGFβRDN cells

Cell therapy

Developed for
prostate cancer
Investigated by
University of Pennsylvania

Trials 1

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03089203 Mar 2017 → Sep 2038 expected prostate cancer University of Pennsylvania Active not recruiting Met primary

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as CART-PSMA-TGFβRDN cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT03089203 ↗
Action Deplete “the induction of tumor eradication in aggressive human prostate cancer mouse models” PMID 29807781 ↗ May 2018
Modality Cell therapy “autologous CAR T cells” NCT03089203 ↗
Route Intravenous “intravenously administered lentivirally transduced dual PSMA-specific/TGFβ-resistant CAR modified autologous T cells” NCT03089203 ↗