Drugs / Visugromab
last change Jul 2026 re-read 2 minutes ago

Visugromab

also known as CTL-002

Monoclonal antibody targets GDF15

Developed for
non-small cell lung carcinoma · cancer · hepatocellular carcinoma · urinary bladder cancer
Investigated by
CatalYm GmbH

Trials 5 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT04725474 Dec 2020 → Apr 2028 expected cancer CatalYm GmbH Active not recruiting No outcome recorded
Phase 24 trials
Phase 2 NCT07219459 Mar 2026 → Sep 2029 expected hepatocellular carcinoma CatalYm GmbH Recruiting No outcome recorded
Phase 2 NCT07246863 Oct 2025 → Oct 2029 expected non-small cell lung carcinoma CatalYm GmbH Recruiting No outcome recorded
Phase 2 NCT07098988 Aug 2025 → Mar 2029 expected non-small cell lung carcinoma CatalYm GmbH Recruiting No outcome recorded
Phase 2 NCT06059547 Sep 2023 → Oct 2025 overdue urinary bladder cancer CatalYm GmbH Active not recruiting No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2/3 NCT07112196 Comparator Apr 2026 → Dec 2029 expected CatalYm GmbH Recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as visugromab ClinicalTrials.gov intervention name — accepted as the source's own label NCT04725474
5

NCT07112196

NCT07219459

NCT06059547

NCT07246863

NCT07098988

Known as CTL-002 “IV visugromab (CTL-002, a monoclonal antibody neutralizing GDF-15) as monotherapy” NCT04725474
2

“anti-GDF-15 antibody Visugromab (CTL-002)” NCT06059547

“Visugromab (CTL-002)” NCT07112196

Action Inhibit “Visugromab, a neutralizing anti-GDF-15 antibody” PMID 42426863 Jul 2026
Modality Monoclonal antibody “visugromab (CTL-002, a monoclonal antibody neutralizing GDF-15)” NCT04725474
Route Intravenous Intravenous (IV) Administration of CTL-002” NCT04725474
Target GDF15 “a monoclonal antibody neutralizing GDF-15” NCT04725474