Drugs / FEZAKINUMAB
last change Jan 2019 re-read 3 minutes ago

FEZAKINUMAB

also known as ILV-094

Monoclonal antibody targets IL22 via inhibition

Developed for
atopic eczema · rheumatoid arthritis · psoriasis
Investigated by
Wyeth is now a wholly owned subsidiary of Pfizer · Icahn School of Medicine at Mount Sinai · Pfizer · Rockefeller University

Trials 4

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT00434746 Jan 2007 → Feb 2008 — Wyeth is now a wholly owned subsidiary of Pfizer Completed No outcome recorded
Phase 1 NCT00447681 Dec 2006 → Nov 2007 — Wyeth is now a wholly owned subsidiary of Pfizer Completed No outcome recorded
Phase 22 trials · 1 missed
Phase 2 NCT01941537 Oct 2013 → Feb 2016 atopic eczema Rockefeller University Completed No outcome recorded
Phase 2 NCT00883896 Jun 2009 → Feb 2011 rheumatoid arthritis Pfizer Completed Missed primary
Comparator or background therapy1 trial
Phase 1 NCT00563524 Comparator Dec 2007 → Jun 2010 psoriasis Wyeth is now a wholly owned subsidiary of Pfizer Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as FEZAKINUMAB ChEMBL registry synonym — accepted as the source's own label CHEMBL1743017 ↗
Known as ILV-094 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00563524 ↗
4

NCT00434746 ↗

NCT00447681 ↗

NCT00883896 ↗

NCT01941537 ↗

Action Inhibit “Interleukin-22 inhibitor” CHEMBL1743017 ↗
Modality Monoclonal antibody — CHEMBL1743017 ↗
Route Intravenous “ILV-094 Administered IV or SC to Healthy Subjects” NCT00434746 ↗
Route Subcutaneous “ILV-094 Administered IV or SC to Healthy Subjects” NCT00434746 ↗
Target IL22 “Interleukin-22 inhibitor” CHEMBL1743017 ↗