Drugs / Packed Red Blood Cells
Trials 2
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT06462027 | Jun 2026 → Jul 2027 | cardiac arrest | NYU Langone Health | Suspended | No outcome recorded |
| Phase 1 | NCT05699005 | Sep 2023 → Mar 2028 expected | anemia, cardiogenic shock | University Hospital, Lille | Recruiting | No outcome recorded |
| Comparator or background therapy4 trials | ||||||
| Phase 2 | NCT03981484 Comparator | Jan 2020 → Oct 2022 | blood coagulation disease, hemorrhagic disease | Bellal A. Joseph, MD, FACS | Unknown | No outcome recorded |
| Phase 3 | NCT04431999 Comparator | Dec 2021 → Oct 2025 | blood coagulation disease | Central Directorate of the Army Health Service | Completed | No outcome recorded |
| — | NCT07677150 Comparator | Oct 2026 → Sep 2028 expected | — | Medical University Innsbruck | Not yet recruiting | No outcome recorded |
| — | NCT02726620 Background | Jan → Dec 2017 | hypotensive disorder | Vanderbilt University Medical Center | Completed | No outcome recorded |
News releases announcing trial results or a regulatory action · 1
| Date | Issuer | Release |
|---|---|---|
| 2019-04-09 | HbO2 Therapeutics LLC | Results Preclinical Results on Hemopure in Kidneys Discarded for Human Transplantation hbo2therapeutics.com ↗
The results showed that Hemopure performed comparably to packed red blood cells while overcoming logistical and clinical issues associated with red blood cell-based solutions including longer shelf half-lives, ease of use and accessibility, and negligible infectious risks. |
All press releases naming this drug 1 release
| Date | Issuer | Release |
|---|---|---|
| 2019-04-09 | HbO2 Therapeutics LLC | Preclinical Results on Hemopure in Kidneys Discarded for Human Transplantation hbo2therapeutics.com ↗ |
Evidence & citations 4 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | packed red blood cells | “The later packs will consist of 3 packed red blood cells (PRBCs), 3 plasma units and 1 dose of platelets.” NCT04431999 ↗ |
| Known as | PRBC | “The purpose of this pilot interventional study is to collect preliminary data on administering packed red blood cell (PRBC) during cardiac arrest (CA).” NCT06462027 ↗ |
| Known as | PRBCs | “The later packs will consist of 3 packed red blood cells (PRBCs), 3 plasma units and 1 dose of platelets.” NCT04431999 ↗1“Packed Red Blood Cells (PRBCs)” NCT05699005 ↗ |
| Route | Intravenous | “500 mL of packed red blood cells administered intravenously 10-20 minutes after CA onset” NCT06462027 ↗ |