Drugs / NEBENTAN
last change Jun 2004 re-read 3 minutes ago

NEBENTAN

also known as YM598 · HE-11 · Nebentan potassium

Small molecule targets EDNRA via inhibition

Developed for
hormone-resistant prostate carcinoma · prostate cancer
Investigated by
Astellas Pharma Inc · Astellas Pharma US, Inc.

Trials 2

200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00050297 ? → Feb 2004 prostate cancer Astellas Pharma Inc Terminated No outcome recorded
Phase 2 NCT00048659 ? → Jun 2004 hormone-resistant prostate carcinoma Astellas Pharma Inc Terminated No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as NEBENTAN ChEMBL registry synonym — accepted as the source's own label CHEMBL2107760 ↗
Known as HE-11 ChEMBL registry synonym — accepted as the source's own label CHEMBL2107760 ↗
Known as Nebentan potassium ChEMBL registry synonym — accepted as the source's own label CHEMBL2107760 ↗
Known as YM598 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00050297 ↗
1

NCT00048659 ↗

Action Inhibit “Endothelin receptor ET-A antagonist” CHEMBL2107760 ↗
Modality Small molecule — CHEMBL2107760 ↗
Target EDNRA “Endothelin receptor ET-A antagonist” CHEMBL2107760 ↗