Drugs / pNGVL4a-SigE7(detox)HSP70
last change Aug 2023 re-read 2 minutes ago

pNGVL4a-SigE7(detox)HSP70

also known as pBI-1

Vaccine

Developed for
cervical cancer · dysplasia of cervix · human papilloma virus infection
Investigated by
National Cancer Institute (NCI) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Trials 1 · a red edge is where a trial was stopped

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT00788164 Nov 2008 → Aug 2023 cervical cancer, dysplasia of cervix, human papilloma virus infection Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as pNGVL4a-sig/E7(detox)/HSP70 “Intramuscular vaccination of women with high-grade cervical intraepithelial neoplasia (CIN2/3) twice with a naked DNA vaccine, pNGVL4a-sig/E7(detox)/HSP70, and a single boost...” PMID 26420854 Sep 2015
2

“HPV16 E7-targeted DNA vaccine pNGVL4a-SigE7(detox)HSP70 (DNA vaccine pBI-1)” PMID 33468698 Jan 2021

NCT00788164

Known as pBI-1 “HPV16 E7-targeted DNA vaccine pNGVL4a-SigE7(detox)HSP70 (DNA vaccine pBI-1)” PMID 33468698 Jan 2021
Modality Vaccine “HPV16 E7-targeted DNA vaccine pNGVL4a-SigE7(detox)HSP70 (DNA vaccine pBI-1)” PMID 33468698 Jan 2021
Route Intramuscular “Given intramuscularly” NCT00788164