Drugs / mRNA HBV/TCR T-cells
last change Jul 2026 re-read 3 minutes ago

mRNA HBV/TCR T-cells

Cell therapy

Developed for
hepatocellular carcinoma
Investigated by
Lion TCR Pte. Ltd.

Trials 1

2023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04745403 May 2022 → Jul 2026 overdue hepatocellular carcinoma Lion TCR Pte. Ltd. Recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as mRNA HBV/TCR T-cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT04745403 ↗
Action Deplete “HBV-specific T cells lysed HBV-producing hepatoma cells in vitro.” PMID 28737510 ↗ Jul 2017
Modality Cell therapy “To develop a more practical and safer approach to cell therapy of HCC, we used electroporation of mRNA encoding anti-HBV TCR.” PMID 23941866 ↗ Aug 2013