Drugs / BIVV003
last change Jul 2025 re-read 2 minutes ago

BIVV003

Cell therapy targets BCL11A

Developed for
sickle cell disease
Investigated by
Sangamo Therapeutics

Trials 1 · a red edge is where a trial was stopped

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT03653247 Mar 2019 → Jul 2025 sickle cell disease Sangamo Therapeutics Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as BIVV003 BIVV003 will be administered as an IV infusion following myeloablative conditioning with busulfan.” NCT03653247
Modality Cell therapy “BIVV003 will then be administered as a 1-time IV infusion of autologous Cluster of Differentiation 34 + Hematopoietic Stem/Progenitor Cell (CD34+HSPC) transfected ex vivo with...” NCT03653247
Route Intravenous “BIVV003 will be administered as an IV infusion following myeloablative conditioning with busulfan.” NCT03653247
Target BCL11A “BIVV003 will then be administered as a 1-time IV infusion of autologous Cluster of Differentiation 34 + Hematopoietic Stem/Progenitor Cell (CD34+HSPC) transfected ex vivo with...” NCT03653247