drugset
Drugs / Brivudine
last change Aug 2025 re-read 9 days ago

Brivudine

also known as Bromovinyldeoxyuridine · BVDU · RP101

targets HSPB1 via inhibition

Developed for
herpes zoster · pancreatic adenocarcinoma
Investigated by
Air Force Military Medical University, China · Beijing Hospital of Traditional Chinese Medicine · Peking University First Hospital · Peking University Third Hospital · Xuanwu Hospital, Beijing

Trials 1

today NCT07099157 · Ph 4
20262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 41 trial
Phase 4 NCT07099157 Aug 2025 → Dec 2026 expected herpes zoster Peking University Third Hospital Recruiting No outcome recorded
Comparator or background therapy1 trial
Phase 2 NCT00550004 Comparator Sep 2007 → Aug 2009 pancreatic adenocarcinoma SciClone Pharmaceuticals Terminated No outcome recorded

Press releases naming this drug 1 release

DateIssuerRelease
2014-08-13 RedHill Biopharma Limited RedHill Biopharma Acquires Option for Phase II Pancreatic Cancer Drug RP101 redhillbio.com ↗

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Brivudine “We reported earlier that RP101 (Bromovinyldeoxyuridine, BVDU, Brivudine) improves the efficacy of chemotherapy in pancreatic cancer.” PMID 21833720 ↗ Jul 2011
1

NCT07099157 ↗
Known as Bromovinyldeoxyuridine “We reported earlier that RP101 (Bromovinyldeoxyuridine, BVDU, Brivudine) improves the efficacy of chemotherapy in pancreatic cancer.” PMID 21833720 ↗ Jul 2011
Known as BVDU “We reported earlier that RP101 (Bromovinyldeoxyuridine, BVDU, Brivudine) improves the efficacy of chemotherapy in pancreatic cancer.” PMID 21833720 ↗ Jul 2011
Known as RP101 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00550004 ↗
Action Inhibit “Here, we report that RP101 binds in vitro to the heat shock protein HSPB1 and inhibits interaction with its binding partners.” PMID 21833720 ↗ Jul 2011
Route Oral “190 mg oral tablet” NCT00550004 ↗
Target HSPB1 “Here, we report that RP101 binds in vitro to the heat shock protein HSPB1 and inhibits interaction with its binding partners.” PMID 21833720 ↗ Jul 2011