Drugs / Troriluzole
Troriluzole
also known as
BHV-4157 · BHV-4157 HYDROCHLORIDE · BHV-4157a · FC-4157 · trigriluzole · TRORILUZOLE HYDROCHLORIDE
Trials 13
News releases announcing trial results or a regulatory action · 1
| Date | Issuer | Release |
|---|---|---|
| 2016-07-05 | Portage Biotech | Regulatory FDA clears Biohaven’s Investigational New Drug Application For BHV-4157 and Portage To Hold Investor Conference Call to Provide Business Update portagebiotech.com ↗ |
All press releases naming this drug 3 releases
| Date | Issuer | Release |
|---|---|---|
| 2022-07-06 | Vigeo Therapeutics, Inc. | Global Coalition for Adaptive Research, Biohaven, and Vigeo Announce Commencement of Biohaven’s Troriluzole and Vigeo’s VT1021 in GBM Agile Trial vigeotx.com ↗ |
| 2016-07-22 | Portage Biotech | Biohaven Commences Clinical Testing of BHV-4157 portagebiotech.com ↗ |
| 2016-07-05 | Portage Biotech | FDA clears Biohaven’s Investigational New Drug Application For BHV-4157 and Portage To Hold Investor Conference Call to Provide Business Update portagebiotech.com ↗ |
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 16 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | troriluzole | “the riluzole prodrug troriluzole (BHV-4157, trigriluzole) and the PD-1 antibody nivolumab” PMID 35780243 ↗ Jul 2022 |
| Known as | BHV-4157 | “The primary purpose of this study was to compare the efficacy of BHV-4157 (Troriluzole) 140 milligrams (mg) once daily versus placebo after 8 weeks of treatment in participants...” NCT02960893 ↗4“Troriluzole (BHV-4157) in Adult Participants With Obsessive Compulsive Disorder” NCT03299166 ↗ “Trigriluzole (FC-4157/BHV-4157)” NCT03229278 ↗ “Troriluzole (BHV-4157)” NCT04708834 ↗ |
| Known as | BHV-4157 HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297586 ↗ |
| Known as | BHV-4157a | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297586 ↗ |
| Known as | FC-4157 | “Trigriluzole (FC-4157/BHV-4157)” NCT03229278 ↗ |
| Known as | trigriluzole | “Given trigriluzole PO” NCT03229278 ↗ |
| Known as | TRORILUZOLE HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297586 ↗ |
| Action | Inhibit | “Trigriluzole may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.” NCT03229278 ↗ |
| Modality | Peptide | “Tripeptide prodrug of Riluzole” NCT06552260 ↗ |
| Route | Oral | “Troriluzole 140 mg capsules orally once daily (QD) for 8 weeks.” NCT02960893 ↗ |