| Phase 1/23 trials |
|
Phase 1/2
|
NCT07708285 |
Jul 2026 → Dec 2028 expected |
NF2-related schwannomatosis, acoustic neuroma, meningioma |
Beijing Tiantan Hospital |
Not yet recruiting
|
No outcome recorded
|
|
Phase 1/2
|
NCT07024394 |
Jun 2025 → Sep 2029 expected |
neurofibromatosis type 1, plexiform neurofibroma |
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. |
Not yet recruiting
|
No outcome recorded
|
|
Phase 1/2
|
NCT04954001 |
Mar 2021 → Feb 2025 overdue |
neurofibromatosis type 1, plexiform neurofibroma |
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. |
Active not recruiting
|
No outcome recorded
|
| Phase 25 trials |
|
Phase 2
|
NCT07713745 |
Jul 2026 → Jun 2036 expected |
NF2-related schwannomatosis, acoustic neuroma, ependymoma, meningioma |
Beijing Tiantan Hospital |
Not yet recruiting
|
No outcome recorded
|
|
Phase 2
|
NCT07562581 |
Jun 2026 → Jun 2029 expected |
metastatic neoplasm, non-small cell lung carcinoma |
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. |
Not yet recruiting
|
No outcome recorded
|
|
Phase 2
|
NCT06913725 |
Feb 2025 → Mar 2026 overdue |
arteriovenous malformations of the brain |
Xuanwu Hospital, Beijing |
Recruiting
|
No outcome recorded
|
|
Phase 2
|
NCT06553365 |
Aug 2024 → Jul 2026 overdue |
nerve sheath neoplasm |
Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
Recruiting
|
No outcome recorded
|
|
Phase 2
|
NCT05997602 |
Sep 2023 → May 2025 overdue |
Langerhans cell histiocytosis |
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. |
Recruiting
|
No outcome recorded
|
| Phase 32 trials |
|
Phase 3
|
NCT07004075 |
Jun 2025 → Apr 2027 expected |
childhood low-grade glioma, diffuse low-grade glioma, MAPK pathway–altered |
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. |
Not yet recruiting
|
No outcome recorded
|
|
Phase 3
|
NCT05913037 |
Jun 2023 → Aug 2025 overdue |
neurofibromatosis type 1, plexiform neurofibroma |
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. |
Active not recruiting
|
No outcome recorded
|
| Phase not applicable2 trials |
| — |
NCT07371182 |
Jun 2026 → Dec 2030 expected |
Langerhans cell histiocytosis |
West China Second University Hospital |
Recruiting
|
No outcome recorded
|
| — |
NCT07431060 |
Feb 2026 → Dec 2030 expected |
multisystem langerhans cell histiocytosis |
West China Second University Hospital |
Recruiting
|
No outcome recorded
|