Drugs / ChAd3-EBO-Z
Trials 3 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT03583606 | Nov 2018 → Jan 2020 | Ebola hemorrhagic fever | National Institute of Allergy and Infectious Diseases (NIAID) | Completed | No outcome recorded |
| Phase 22 trials | ||||||
| Phase 2 | NCT02485301 | Jul 2015 → Dec 2016 | viral infectious disease | GlaxoSmithKline | Completed | No outcome recorded |
| Phase 2 | NCT02344407 | Jan 2015 → Jun 2016 | Ebola hemorrhagic fever | National Institute of Allergy and Infectious Diseases (NIAID) | Completed | No outcome recorded |
Also used as a comparator or background therapy in 3 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1 | NCT02495246 Comparator | Sep 2015 → Aug 2017 | Ebola hemorrhagic fever | University of Oxford | Completed | No outcome recorded |
| Phase 1 | NCT02485912 Comparator | Jul 2015 → Jan 2016 | Ebola hemorrhagic fever | University of Oxford | Completed | No outcome recorded |
| Phase 1 | NCT02451891 Comparator | May 2015 → Aug 2017 | Ebola hemorrhagic fever | University of Oxford | Terminated | No outcome recorded |
Evidence & citations 4 cited values
Every value below carries the sentence it was read from. 8 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | ChAd3-EBO-Z | “We initiated a randomized, placebo-controlled, phase 3 trial of the chimpanzee adenovirus 3 vaccine (ChAd3-EBO-Z) and the recombinant vesicular stomatitis virus vaccine...” PMID 29020589 ↗ Oct 20177“recombinant chimpanzee adenovirus type 3 vectored Ebola Zaire vaccine (ChAd3-EBO-Z) followed by MVA-EBO-Z.” PMID 30407513 ↗ Apr 2019 |
| Known as | GSK3390107A | “GlaxoSmithKline (GSK) Biologicals' investigational recombinant chimpanzee adenovirus Type 3-vectored Ebola Zaire vaccine (ChAd3-EBO-Z) (GSK3390107A)” NCT02485301 ↗ |
| Modality | Vaccine | “The ChAd3-EBO Z vaccine is comprised of a ChAd3 vector with a DNA fragment insert that encodes the Ebola virus glycoprotein, which is expressed on the virion surface and is...” NCT02344407 ↗ |
| Route | Intramuscular | “A single dose administrated intramuscular” NCT02485301 ↗ |