Drugs / HEXASODIUM PHYTATE
HEXASODIUM PHYTATE
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Filed | Other | — | — | — | “The MAA for Switzerland, Australia, Canada and Singapore was submitted in Q2 2021, with a decision expected in Q2 2022.” csl.com ↗ |
Trials 3
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 22 trials · 1 met primary | ||||||
| Phase 2 | NCT02966028 | Nov 2016 → Aug 2019 | calcinosis, coronary atherosclerosis, end stage renal failure | Sanifit Therapeutics S. A. | Completed | Met primary |
| Phase 2 | NCT02790073 | May 2016 → Nov 2017 | calciphylaxis | Sanifit Therapeutics S. A. | Completed | No outcome recorded |
| Phase 31 trial · 1 missed | ||||||
| Phase 3 | NCT04195906 | Feb 2020 → Oct 2022 | calciphylaxis | Sanifit Therapeutics S. A. | Completed | Missed primary |
Evidence & citations 8 cited values
Every value below carries the sentence it was read from. 8 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | HEXASODIUM PHYTATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL4802218 ↗ |
| Known as | hexasodium fytate | “infusion of hexasodium fytate (SNF472), the hexasodium salt of inositol hexaphosphate, for 52 weeks thrice weekly during hemodialysis significantly reduced progression of...” PMID 38384289 ↗ Feb 2024 |
| Known as | myo-inositol hexaphosphate | “SNF472, intravenous myo-inositol hexaphosphate, selectively inhibits the formation and growth of hydroxyapatite.” PMID 31707860 ↗ Nov 2019 |
| Known as | Phytate hexasodium | ChEMBL registry synonym — accepted as the source's own label CHEMBL4802218 ↗ |
| Known as | SNF472 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04195906 ↗ |
| Action | Inhibit | “an inhibitor of vascular calcification” PMID 39252867 ↗ Aug 2024 |
| Modality | Small molecule | “the hexasodium salt of inositol hexaphosphate” PMID 38384289 ↗ Feb 2024 |
| Route | Intravenous | “intravenous administration of SNF472 (300 or 600 mg) during hemodialysis” PMID 33835939 ↗ Apr 2021 |