Drugs / Canocapavir
last change Aug 2025 re-read 2 minutes ago

Canocapavir

also known as ZM-H1505R

Small molecule

Developed for
chronic hepatitis B virus infection
Investigated by
Shanghai Zhimeng Biopharma, Inc. · Tigermed Consulting Co., Ltd

Trials 4 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT05470829 May → Nov 2021 chronic hepatitis B virus infection Shanghai Zhimeng Biopharma, Inc. Completed No outcome recorded
Phase 1 NCT04220801 Feb → Nov 2020 Shanghai Zhimeng Biopharma, Inc. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05484466 Nov → Dec 2022 chronic hepatitis B virus infection Shanghai Zhimeng Biopharma, Inc. Unknown No outcome recorded
Phase 31 trial
Phase 3 NCT07095855 Aug 2025 → Jan 2028 expected chronic hepatitis B virus infection Shanghai Zhimeng Biopharma, Inc. Not yet recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as Canocapavir “A Multicenter, Randomized, Double-Blind, Placebo-Controlled and Open-Label Extension Phase III Study to Evaluate the Efficacy and Safety of ZM-H1505R (Canocapavir) in...” NCT07095855
2

Canocapavir (ZM-H1505R) is a small-molecule hepatitis B virus capsid assembly modulator with a novel pyrazole structure.” PMID 39132049 Jan 2023

“ZM-H1505R (Canocapavir), a chemically unique HBV CpTA, were evaluated in patients with CHB.” PMID 36927420 Mar 2023

Known as ZM-H1505R ClinicalTrials.gov intervention name — accepted as the source's own label NCT05484466
3

NCT07095855

NCT04220801

NCT05470829

Modality Small molecule “Canocapavir (ZM-H1505R) is a small-molecule hepatitis B virus capsid assembly modulator” PMID 39132049 Jan 2023
Route Oral “following oral administration in healthy subjects” NCT04220801