Drugs / SGN-30

Trials 7 · a red edge is where a trial was stopped

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/22 trials
Phase 1/2 NCT00354107 Jan 2007 → Jan 2010 anaplastic large cell lymphoma National Cancer Institute (NCI) Terminated No outcome recorded
Phase 1/2 NCT00051597 ? → Aug 2003 B-cell non-Hodgkin lymphoma, Hodgkins lymphoma, Kaposi's sarcoma, primary cutaneous T-cell lymphoma Seagen Inc. Completed No outcome recorded
Phase 25 trials
Phase 2 NCT02623920 Dec 2015 → May 2017 chronic lymphocytic leukemia/small lymphocytic lymphoma, follicular lymphoma, high grade B-cell lymphoma, marginal zone lymphoma +2 University of Arizona Withdrawn No outcome recorded
Phase 2 NCT00365274 Aug 2006 → May 2010 anaplastic large cell lymphoma National Cancer Institute (NCI) Terminated No outcome recorded
Phase 2 NCT00337194 Apr 2006 → Sep 2008 Hodgkin's lymphoma, lymphocytic depletion, Hodgkin's lymphoma, mixed cellularity, adult nodular lymphocyte predominant Hodgkin lymphoma, nodular sclerosis classical Hodgkin lymphoma National Cancer Institute (NCI) Completed No outcome recorded
Phase 2 NCT00099255 Sep 2004 → Feb 2007 lymphoma Seagen Inc. Completed No outcome recorded
Phase 2 NCT00079755 Feb 2004 → Dec 2006 anaplastic large cell lymphoma Seagen Inc. Completed No outcome recorded

Press releases naming this drug 1 release

DateIssuerRelease
2024-06-01 Pfizer Takeda and Pfizer Announce Four-Year Results from Positive Phase 3 HD21 Trial of Additional ADCETRIS® (brentuximab vedotin) Combination in Frontline Hodgkin Lymphoma pfizer.com

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as SGN-30 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00079755
5

NCT00354107

NCT00099255

NCT00337194

NCT00051597

NCT00365274

Known as Brentuximab ClinicalTrials.gov intervention name — accepted as the source's own label NCT02623920
Action Inhibit “Monoclonal antibodies, such as SGN-30, may interfere with the ability of cancer cells to grow and spread.” NCT00337194
Modality Monoclonal antibody “Phase 1 testing of SGN-30, a chimeric monoclonal antibody for the treatment of CD30(+) malignancies, was conducted in a multicenter study.” PMID 18079362 Dec 2007
Route Intravenous “received 6 weekly doses of intravenous SGN-30 at 4 dose levels (2, 4, 8, or 12 mg/kg).” PMID 18079362 Dec 2007