Drugs / GSK2245035
last change Dec 2019 re-read 2 minutes ago

GSK2245035

Small molecule targets TLR7 via activation

Developed for
asthma · allergic disease · seasonal allergic rhinitis
Investigated by
GlaxoSmithKline · PATH

Trials 5 · a red edge is where a trial was stopped

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01480271 May → Sep 2011 seasonal allergic rhinitis GlaxoSmithKline Completed No outcome recorded
Phase 24 trials
Phase 2 NCT03707678 Jan → Dec 2019 asthma GlaxoSmithKline Withdrawn No outcome recorded
Phase 2 NCT02833974 Dec 2016 → Feb 2018 asthma GlaxoSmithKline Completed No outcome recorded
Phase 2 NCT01788813 Mar 2013 → Aug 2014 asthma GlaxoSmithKline Completed No outcome recorded
Phase 2 NCT01607372 Apr 2012 → Sep 2013 allergic disease GlaxoSmithKline Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as GSK2245035 “Intranasal Dosing With GSK2245035, a TLR7 Agonist” NCT01480271
4

NCT01788813

NCT03707678

NCT01607372

NCT02833974

Action Activate “TLR7 agonist” NCT01480271
Modality Small molecule CHEMBL4297492
Route Intranasal “administered intranasally” NCT01480271
Target TLR7 TLR7 agonist” NCT01480271