Drugs / IMM-1-104
last change Jun 2026 re-read 9 days ago

IMM-1-104

Developed for
cutaneous melanoma · non-small cell lung carcinoma · pancreatic adenocarcinoma
Investigated by
Immuneering Corporation

Trials 1

2023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT05585320 Oct 2022 → Jun 2026 overdue cutaneous melanoma, non-small cell lung carcinoma, pancreatic adenocarcinoma Immuneering Corporation Active not recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 2

DateIssuerRelease
2026-05-21 Immuneering Corporation Results Immuneering Reports 17.3 Months Median Overall Survival in First-Line Metastatic Pancreatic Cancer Patients Treated with Atebimetinib Plus Chemotherapy immuneering.com ↗
Immuneering Corporation (Nasdaq: IMRX), a late-stage clinical oncology company focused on keeping cancer patients alive and helping them thrive, today reported a 17.3-month median overall survival (OS) in first-line metastatic pancreatic cancer patients treated in its Phase 2a clinical trial evaluating atebimetinib (IMM-1-104) plus modified gemcitabine/nab-paclitaxel (mGnP), as of the April 24, 2026 data cutoff date.
2026-01-07 Immuneering Corporation Results Immuneering Announces Exceptional 64% Overall Survival At 12 Months in First-Line Pancreatic Cancer Patients Treated with Atebimetinib + mGnP immuneering.com ↗
Immuneering Corporation (Nasdaq: IMRX), a late-stage clinical oncology company focused on keeping cancer patients alive and helping them thrive, today announced positive updated overall survival (OS) and safety data from its ongoing Phase 2a trial of atebimetinib (IMM-1-104) in combination with modified gemcitabine/nab-paclitaxel (mGnP) in first-line pancreatic cancer patients (N=34), with over 13 months median follow up time.

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as IMM-1-104 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05585320 ↗
Action Inhibit “a Novel Oral Dual MEK1/2 Inhibitor” NCT05585320 ↗
Route Oral “Once-daily, oral IMM-1-104 dose” NCT05585320 ↗