Drugs / ZVS203e
last change Apr 2026 re-read 3 minutes ago

ZVS203e

CRISPR / gene editing targets RHO via inhibition

Developed for
retinitis pigmentosa
Investigated by
Chigenovo Co., Ltd · Peking University Third Hospital

Trials 2

2024202520262027202820292030
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT05805007 Sep 2023 → Apr 2026 retinitis pigmentosa Peking University Third Hospital Unknown No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT06952842 Aug 2025 → Jun 2030 expected retinitis pigmentosa Chigenovo Co., Ltd Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as ZVS203e ClinicalTrials.gov intervention name — accepted as the source's own label NCT06952842 ↗
1

NCT05805007 ↗

Action Inhibit “silences RHO mutant protein expression” NCT05805007 ↗
Modality CRISPR / gene editing “CRISPR/Cas9 editing system” NCT05805007 ↗
Route Other “subretinal injection” NCT05805007 ↗
Target RHO “silences RHO mutant protein expression” NCT05805007 ↗