Drugs / TAURODEOXYCHOLIC ACID
last change Jun 2026 re-read 3 minutes ago

TAURODEOXYCHOLIC ACID

Small molecule targets TNF via inhibition

Developed for
atopic eczema · infectious disease with sepsis
Investigated by
Shaperon · Kukjeon Pharmaceutical Co.,Ltd.

Trials 4

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT06533878 Sep 2023 → Dec 2024 overdue dementia Kukjeon Pharmaceutical Co.,Ltd. Enrolling by invitation No outcome recorded
Phase 1 NCT04255979 Dec 2019 → Jun 2020 infectious disease with sepsis Shaperon Completed No outcome recorded
Phase 1 NCT03492398 Jan 2018 → Mar 2019 atopic eczema Shaperon Completed No outcome recorded
Phase 21 trial · 1 missed
Phase 2 NCT04530643 Aug 2020 → Sep 2021 atopic eczema Shaperon Completed Missed primary

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2026-06-24 Shaperon Results [보도자료] 샤페론, 누겔 글로벌 임상 2b상 결과 추가 분석 착수… “보습제 등 외부 요인 영향 가능성” shaperon.com ↗
수령한 결과에 따르면 누겔 투여군과 위약군 간 1차 평가지표 차이가 사전에 설정된 통계적 유의수준(양측성 0.025)을 충족하지 못한 것으로 확인됐다.

Evidence & citations 10 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as TAURODEOXYCHOLIC ACID ChEMBL registry synonym — accepted as the source's own label CHEMBL412272 ↗
Known as Deoxycholyltaurine ChEMBL registry synonym — accepted as the source's own label CHEMBL412272 ↗
Known as HY209 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04530643 ↗
3

NCT06533878 ↗

NCT03492398 ↗

NCT04255979 ↗

Known as J339.140J ChEMBL registry synonym — accepted as the source's own label CHEMBL412272 ↗
Known as Taurodesoxycholic acid ChEMBL registry synonym — accepted as the source's own label CHEMBL412272 ↗
Known as Tudcabil ChEMBL registry synonym — accepted as the source's own label CHEMBL412272 ↗
Action Activate “The GPCR19 agonist, HY209” NCT03492398 ↗
Modality Small molecule — CHEMBL412272 ↗
Route Intravenous “after intravenous administration” NCT04255979 ↗
Target TNF “inhibition of release of Tumor Necrosis Factor(TNF)-α” NCT06533878 ↗