Drugs / Rivoglitazone
last change Nov 2012 re-read 2 minutes ago

Rivoglitazone

Small molecule targets PPARG via activation

Developed for
type 2 diabetes mellitus · dry eye syndrome
Investigated by
Daiichi Sankyo · Santen Inc.

Trials 7 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT01118754 Apr → Dec 2010 dry eye syndrome Santen Inc. Completed No outcome recorded
Phase 23 trials
Phase 2 NCT01468168 Oct 2011 → Nov 2012 dry eye syndrome Santen Inc. Completed No outcome recorded
Phase 2 NCT00575874 Aug 2007 → Jun 2008 type 2 diabetes mellitus Daiichi Sankyo Completed No outcome recorded
Phase 2 NCT00575471 Jul 2007 → Mar 2008 type 2 diabetes mellitus Daiichi Sankyo Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT00143520 Dec 2004 → Dec 2005 type 2 diabetes mellitus Daiichi Sankyo Completed No outcome recorded
Phase 32 trials
Phase 3 NCT00571519 Nov 2007 → May 2008 type 2 diabetes mellitus Daiichi Sankyo Terminated No outcome recorded
Phase 3 NCT00484198 Apr 2007 → Feb 2009 type 2 diabetes mellitus Daiichi Sankyo Completed No outcome recorded

Evidence & citations 10 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as Rivoglitazone ClinicalTrials.gov intervention name — accepted as the source's own label NCT00575874
4

NCT00571519

NCT00575471

NCT00484198

NCT00143520

Known as CS-011 “A Randomized, Double-blind, Double-dummy, Placebo-controlled 26-week Dose-response Study of Rivoglitazone HCl (CS-011) With Active Comparator (Pioglitazone HCl) in Subjects...” NCT00143520
1

“A Randomized, Double-Blind, Placebo-Controlled 12-Week Dose-Response Study of Rivoglitazone (CS-011) in Patients With Type 2 Diabetes.” NCT00575471

Known as DE-101 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01468168
1

NCT01118754

Known as R 106056 ChEMBL registry synonym — accepted as the source's own label CHEMBL2104753
Known as Rivoglitazona ChEMBL registry synonym — accepted as the source's own label CHEMBL2104753
Known as Rivoglitazone HCl “A Randomized, Double-blind, Double-dummy, Placebo-controlled 26-week Dose-response Study of Rivoglitazone HCl (CS-011) With Active Comparator (Pioglitazone HCl) in Subjects...” NCT00143520
1

rivoglitazone HCl 0.5mg” NCT00571519

Action Activate “Peroxisome proliferator-activated receptor gamma agonist” CHEMBL2104753
Modality Small molecule “rivoglitazone, a novel thiazolidinedione” PMID 20370378 Jun 2010
Route Oral “1.0 mg tablet administered orally, once daily” NCT00484198
Target PPARG “Peroxisome proliferator-activated receptor gamma agonist” CHEMBL2104753