Drugs / JR-171
last change May 2025 re-read 3 minutes ago

JR-171

also known as lepunafusp alfa

Protein / enzyme biologic

Developed for
mucopolysaccharidosis type 1
Investigated by
JCR Pharmaceuticals Co., Ltd.

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT04453085 Oct 2021 → May 2025 mucopolysaccharidosis type 1 JCR Pharmaceuticals Co., Ltd. Completed No outcome recorded
Phase 1/2 NCT04227600 Sep 2020 → Aug 2022 mucopolysaccharidosis type 1 JCR Pharmaceuticals Co., Ltd. Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as JR-171 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04227600 ↗
1

NCT04453085 ↗

Known as lepunafusp alfa “We have developed a novel genetically modified protein consisting of IDUA fused with humanized anti-human transferrin receptor antibody (lepunafusp alfa; JR-171), which has...” PMID 38204164 ↗ Jan 2024
Modality Protein / enzyme biologic “a novel genetically modified protein consisting of IDUA fused with humanized anti-human transferrin receptor antibody” PMID 38204164 ↗ Jan 2024
Route Intravenous “IV infusion” NCT04227600 ↗