Drugs / pegylated carboxyhemoglobin bovine
last change Feb 2025 re-read 2 minutes ago

pegylated carboxyhemoglobin bovine

also known as SANGUINATE · PP-007

Protein / enzyme biologic

Developed for
sickle cell disease · disease related to solid organ transplantation · anemia · brain ischemia · chronic kidney disease · ischemic stroke · ulcer of lower limbs
Investigated by
Prolong Pharmaceuticals

Trials 11 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT04677777 Apr 2024 → Feb 2025 ischemic stroke Prolong Pharmaceuticals Completed No outcome recorded
Phase 1 NCT02754999 Mar 2016 → May 2017 anemia Prolong Pharmaceuticals Completed No outcome recorded
Phase 1 NCT02437422 Jun → Nov 2015 chronic kidney disease Prolong Pharmaceuticals Completed No outcome recorded
Phase 1 NCT01848925 May 2013 → Jul 2014 sickle cell disease Prolong Pharmaceuticals Completed No outcome recorded
Phase 1 NCT01847222 May 2013 → May 2014 Prolong Pharmaceuticals Terminated No outcome recorded
Phase 25 trials
Phase 2 NCT02411708 Nov 2016 → Dec 2017 sickle cell disease Prolong Pharmaceuticals Completed No outcome recorded
Phase 2 NCT02672540 Jul 2016 → May 2017 sickle cell disease Prolong Pharmaceuticals Completed No outcome recorded
Phase 2 NCT02600390 Mar → Oct 2016 ulcer of lower limbs Prolong Pharmaceuticals Completed No outcome recorded
Phase 2 NCT02658162 Feb 2016 → Oct 2018 disease related to solid organ transplantation Prolong Pharmaceuticals Withdrawn No outcome recorded
Phase 2 NCT02323685 Dec 2014 → Jun 2016 brain ischemia Prolong Pharmaceuticals Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT02490202 Aug 2015 → Aug 2016 disease related to solid organ transplantation Prolong Pharmaceuticals Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 11 sources stand behind the page.

FieldValueCited text
Known as pegylated carboxyhemoglobin bovine “SANGUINATE (pegylated carboxyhemoglobin bovine)” NCT02600390
Known as PP-007 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04677777
Known as SANGUINATE SANGUINATE™ in Sickle Cell Disease Associated Leg Ulcer” NCT02600390
10

NCT01848925

NCT02437422

NCT02323685

NCT02658162

NCT02411708

NCT02754999

NCT02600390

NCT02672540

NCT02490202

NCT01847222

Modality Protein / enzyme biologic “Single infusion of SANGUINATE (pegylated carboxyhemogloblin)” NCT02323685
Route Intravenous “40 mg/mL intravenous infusion.” NCT01848925