drugset
Drugs / pegylated carboxyhemoglobin bovine
last change Feb 2025 re-read 9 days ago

pegylated carboxyhemoglobin bovine

also known as SANGUINATE · PP-007

Protein / enzyme biologic

Developed for
sickle cell disease · disease related to solid organ transplantation · anemia · brain ischemia · chronic kidney disease · ischemic stroke · ulcer of lower limbs
Investigated by
Prolong Pharmaceuticals

Trials 11

today NCT04677777 · Ph 1 NCT02411708 · Ph 2 NCT02672540 · Ph 2 NCT02754999 · Ph 1 NCT02600390 · Ph 2 NCT02658162 · Ph 2 NCT02490202 · Ph 2/3 NCT02437422 · Ph 1 NCT02323685 · Ph 2 NCT01848925 · Ph 1 NCT01847222 · Ph 1
201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT04677777 Apr 2024 → Feb 2025 ischemic stroke Prolong Pharmaceuticals Completed No outcome recorded
Phase 1 NCT02754999 Mar 2016 → May 2017 anemia Prolong Pharmaceuticals Completed No outcome recorded
Phase 1 NCT02437422 Jun → Nov 2015 chronic kidney disease Prolong Pharmaceuticals Completed No outcome recorded
Phase 1 NCT01848925 May 2013 → Jul 2014 sickle cell disease Prolong Pharmaceuticals Completed No outcome recorded
Phase 1 NCT01847222 May 2013 → May 2014 — Prolong Pharmaceuticals Terminated No outcome recorded
Phase 25 trials
Phase 2 NCT02411708 Nov 2016 → Dec 2017 sickle cell disease Prolong Pharmaceuticals Completed No outcome recorded
Phase 2 NCT02672540 Jul 2016 → May 2017 sickle cell disease Prolong Pharmaceuticals Completed No outcome recorded
Phase 2 NCT02600390 Mar → Oct 2016 ulcer of lower limbs Prolong Pharmaceuticals Completed No outcome recorded
Phase 2 NCT02658162 Feb 2016 → Oct 2018 disease related to solid organ transplantation Prolong Pharmaceuticals Withdrawn No outcome recorded
Phase 2 NCT02323685 Dec 2014 → Jun 2016 brain ischemia Prolong Pharmaceuticals Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT02490202 Aug 2015 → Aug 2016 disease related to solid organ transplantation Prolong Pharmaceuticals Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 11 sources stand behind the page.

FieldValueCited text
Known as pegylated carboxyhemoglobin bovine “SANGUINATE (pegylated carboxyhemoglobin bovine)” NCT02600390 ↗
Known as PP-007 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04677777 ↗
Known as SANGUINATE “SANGUINATE™ in Sickle Cell Disease Associated Leg Ulcer” NCT02600390 ↗
10

NCT02600390 ↗

NCT01848925 ↗

NCT02323685 ↗

NCT02490202 ↗

NCT01847222 ↗

NCT02411708 ↗

NCT02672540 ↗

NCT02754999 ↗

NCT02437422 ↗

NCT02658162 ↗
Modality Protein / enzyme biologic “Single infusion of SANGUINATE (pegylated carboxyhemogloblin)” NCT02323685 ↗
Route Intravenous “40 mg/mL intravenous infusion.” NCT01848925 ↗