Drugs / gavocabtagene autoleucel
last change Nov 2024 re-read 3 minutes ago

gavocabtagene autoleucel

English name Gavocabtagene autoleucel
also known as gavo-cel · TC-210 T cells

Cell therapy

Developed for
cholangiocarcinoma · malignant mesothelioma · non-small cell lung carcinoma · ovarian serous adenocarcinoma · peritoneal mesothelioma · pleural mesothelioma
Investigated by
Bristol-Myers Squibb · TCR2 Therapeutics

Trials 1

2020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT03907852 Apr 2019 → Nov 2024 overdue cholangiocarcinoma, malignant mesothelioma, non-small cell lung carcinoma, ovarian serous adenocarcinoma +2 TCR2 Therapeutics Active not recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as gavocabtagene autoleucel “The T cell receptor fusion construct (TRuC) gavocabtagene autoleucel (gavo-cel) consists of single-domain anti-mesothelin antibody that integrates into the endogenous T cell...” PMID 37501016 ↗ Jul 2023
Known as gavo-cel ClinicalTrials.gov intervention name — accepted as the source's own label NCT03907852 ↗
Known as TC-210 T cells ChEMBL registry synonym — accepted as the source's own label CHEMBL4802259 ↗
Modality Cell therapy “Gavocabtagene autoleucel (gavo-cel; TC-210) is a novel cell therapy that consists of autologous genetically engineered T cells expressing a single-domain antibody that...” NCT03907852 ↗