Drugs / QLC1101
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QLC1101

Small molecule targets KRAS via inhibition

Developed for
colorectal cancer · malignant pancreatic neoplasm · neoplasm · non-small cell lung carcinoma
Investigated by
Qilu Pharmaceutical Co., Ltd.

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT06980909 Jun → Aug 2025 overdue Qilu Pharmaceutical Co., Ltd. Not yet recruiting No outcome recorded
Phase 1 NCT06403735 Apr 2024 → May 2026 overdue colorectal cancer, malignant pancreatic neoplasm, non-small cell lung carcinoma Qilu Pharmaceutical Co., Ltd. Recruiting No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT06949761 Jun 2025 → Sep 2026 expected neoplasm Qilu Pharmaceutical Co., Ltd. Not yet recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as QLC1101 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06949761
2

NCT06980909

NCT06403735

Action Inhibit inhibit mutant KRAS-dependent signal transduction” NCT06403735
Modality Small molecule “QLC1101 is an innovative small molecule inhibitor targeting KRAS G12D” NCT06403735
Route Oral “administration route of oral administration” NCT06403735
Target KRAS “specifically binding to the KRAS G12D target” NCT06403735