Drugs / QLC1101
last change Sep 2026 re-read 9 days ago

QLC1101

Small molecule targets KRAS via inhibition

Developed for
colorectal cancer · malignant pancreatic neoplasm · neoplasm · non-small cell lung carcinoma
Investigated by
Qilu Pharmaceutical Co., Ltd.

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT06980909 Jun → Aug 2025 overdue — Qilu Pharmaceutical Co., Ltd. Not yet recruiting No outcome recorded
Phase 1 NCT06403735 Apr 2024 → May 2026 overdue colorectal cancer, malignant pancreatic neoplasm, non-small cell lung carcinoma Qilu Pharmaceutical Co., Ltd. Recruiting No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT06949761 Jun 2025 → Sep 2026 overdue neoplasm Qilu Pharmaceutical Co., Ltd. Not yet recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as QLC1101 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06403735 ↗
2

NCT06949761 ↗

NCT06980909 ↗

Action Inhibit “inhibit mutant KRAS-dependent signal transduction” NCT06403735 ↗
Modality Small molecule “QLC1101 is an innovative small molecule inhibitor targeting KRAS G12D” NCT06403735 ↗
Route Oral “administration route of oral administration” NCT06403735 ↗
Target KRAS “specifically binding to the KRAS G12D target” NCT06403735 ↗