Drugs / FRUNEXIAN
last change May 2025 re-read 3 minutes ago

FRUNEXIAN

Small molecule

Developed for
COVID-19
Investigated by
eXIthera Pharmaceuticals · CPR Pharma Services Pty Ltd, Australia · IDT CMAX Clinical Trials · Syneos Health

Trials 2

20172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT02914353 Jul 2016 → May 2017 osteoarthritis, knee eXIthera Pharmaceuticals Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05040776 Oct 2023 → May 2024 COVID-19, thrombocytopenia eXIthera Pharmaceuticals Withdrawn No outcome recorded Stop: Business

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as FRUNEXIAN ChEMBL registry synonym — accepted as the source's own label CHEMBL5314583 ↗
Known as EP-7041 “This First-In-Human study will evaluate the safety and tolerability, pharmacokinetic profile, and pharmacodynamic effects of EP-7041, a novel Factor XIa inhibitor, following IV...” NCT02914353 ↗
2

NCT05040776 ↗

NCT02914353 ↗

Known as EP-7041 HCl ChEMBL registry synonym — accepted as the source's own label CHEMBL5314583 ↗
Known as FRUNEXIAN HYDROCHLORIDE ChEMBL registry synonym — accepted as the source's own label CHEMBL5314583 ↗
Action Inhibit “a novel Factor XIa inhibitor” NCT02914353 ↗
Modality Small molecule — CHEMBL5314583 ↗
Route Intravenous “following IV administration” NCT02914353 ↗