Drugs / VLX-1005
last change Nov 2025 re-read 9 days ago

VLX-1005

also known as ML-355

Small molecule

Developed for
heparin-induced thrombocytopenia
Investigated by
Veralox Therapeutics · Celerion

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT05325346 Mar → Apr 2022 heparin-induced thrombocytopenia Veralox Therapeutics Completed No outcome recorded
Phase 1 NCT04783545 Mar 2021 → Jan 2022 — Veralox Therapeutics Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05785819 Sep 2023 → Nov 2025 heparin-induced thrombocytopenia, thrombocytopenia due to immune destruction Veralox Therapeutics Terminated No outcome recorded Stop: Business

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as VLX-1005 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05325346 ↗
2

NCT04783545 ↗

NCT05785819 ↗

Known as ML-355 ChEMBL registry synonym — accepted as the source's own label CHEMBL3113165 ↗
Action Inhibit “VLX-1005 is a drug that blocks the 12-lipoxygenase (12-LOX) pathway” NCT05785819 ↗
Modality Small molecule — CHEMBL3113165 ↗
Route Intravenous “following intravenous (IV) administration” NCT04783545 ↗