Drugs / VLX-1005
last change Nov 2025 re-read 2 minutes ago

VLX-1005

also known as ML-355

Small molecule

Developed for
heparin-induced thrombocytopenia
Investigated by
Veralox Therapeutics · Celerion

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT05325346 Mar → Apr 2022 heparin-induced thrombocytopenia Veralox Therapeutics Completed No outcome recorded
Phase 1 NCT04783545 Mar 2021 → Jan 2022 Veralox Therapeutics Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05785819 Sep 2023 → Nov 2025 heparin-induced thrombocytopenia, thrombocytopenia due to immune destruction Veralox Therapeutics Terminated No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as VLX-1005 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04783545
2

NCT05785819

NCT05325346

Known as ML-355 ChEMBL registry synonym — accepted as the source's own label CHEMBL3113165
Action Inhibit “VLX-1005 is a drug that blocks the 12-lipoxygenase (12-LOX) pathway” NCT05785819
Modality Small molecule CHEMBL3113165
Route Intravenous “following intravenous (IV) administration” NCT04783545