Drugs / ABBV-428
last change Feb 2021 re-read 3 minutes ago

ABBV-428

targets CD40 via activation

Investigated by
AbbVie

Trials 1

20172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02955251 Nov 2016 → Oct 2019 — AbbVie Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as ABBV-428 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02955251 ↗
Action Activate “tumor microenvironment-dependent CD40 activation” PMID 33608377 ↗ Feb 2021
Route Intravenous “ABBV-428 was administered intravenously every 2 weeks to patients with advanced solid tumors.” PMID 33608377 ↗ Feb 2021
Target CD40 “ABBV-428, a first-in-class, mesothelin-targeted, bispecific antibody designed for tumor microenvironment-dependent CD40 activation” PMID 33608377 ↗ Feb 2021