Drugs / ChAdOx1-S
last change May 2024 re-read 2 minutes ago

ChAdOx1-S

also known as Vaxzevria

Vaccine

Developed for
COVID-19
Investigated by
Bill and Melinda Gates Foundation · D'Or Institute for Research and Education · Instituto Fernandes Figueira

Trials 2 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT05087368 Dec 2021 → Apr 2022 COVID-19 D'Or Institute for Research and Education Unknown No outcome recorded
Phase 31 trial
Phase 3 NCT05812586 Mar → Jun 2023 COVID-19 D'Or Institute for Research and Education Unknown No outcome recorded
Also used as a comparator or background therapy in 2 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT05293665 Comparator Mar → Nov 2022 Vaxxinity, Inc. Unknown No outcome recorded
Phase 3 NCT05007951 Comparator Aug 2021 → Oct 2023 COVID-19 SK Bioscience Co., Ltd. Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as ChAdOx1-S “randomized 2:1:1 to receive either recombinant protein (SCB-2019, Clover), adenovirus-vector (ChAdOx1-S, AstraZeneca/Fiocruz), or mRNA (BNT162b2, Pfizer/Wyeth).” PMID 38762360 May 2024
3

NCT05007951

NCT05087368

NCT05293665

Known as Vaxzevria “ChAdOx1-S (Vaxzevria, AstraZeneca)” PMID 37711219 Sep 2023
Modality Vaccine “GBP510 (Test vaccine) and ChAdOx1-S (Control vaccine)” NCT05007951
Route Intramuscular “ChAdOx1-S vaccine, 0.5 mL suspension with approximately 5.0 × 10˄10 viral particles, intramuscular injection” NCT05293665