Drugs / BD114VLP
last change Sep 2025 re-read 3 minutes ago

BD114VLP

also known as BD114

CRISPR / gene editing

Developed for
cervical intraepithelial neoplasia grade 2/3
Investigated by
Obstetrics & Gynecology Hospital of Fudan University · Shanghai BDgene Co., Ltd.

Trials 1

PhaseRegistry idDatesIndicationSponsorStatusOutcome
— NCT07170254 Sep 2025 → Dec 2026 expected cervical intraepithelial neoplasia grade 2/3 Shanghai BDgene Co., Ltd. Recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as BD114VLP ClinicalTrials.gov intervention name — accepted as the source's own label NCT07170254 ↗
Known as BD114 “CRISPR/Cas9 instantaneous gene editing therapy, called BD114VLP (also BD114) which is a developing product of gene therapy from modified third-generation integrated defective...” NCT07170254 ↗
Action Inhibit “It works to knock out or knock down HPV-16 E6/E7 genes integrated in HSIL cell genome” NCT07170254 ↗
Modality CRISPR / gene editing “CRISPR/Cas9 instantaneous gene editing therapy” NCT07170254 ↗
Route Other “A single dosing BD114 injection by topical intraepithelial injection of HSIL lesion.” NCT07170254 ↗
Route Topical “A single dosing BD114 injection by topical intraepithelial injection of HSIL lesion.” NCT07170254 ↗